About the Authors

Keith S. Kaye

Affiliation Wayne State University and Detroit Medical Center, Detroit, Michigan, United States of America

Dipen A. Patel

Affiliation Pharmerit International, Bethesda, Maryland, United States of America

Jennifer M. Stephens

jstephens@pharmerit.com

Affiliation Pharmerit International, Bethesda, Maryland, United States of America

Alexandra Khachatryan

Affiliation Pharmerit International, Bethesda, Maryland, United States of America

Ayush Patel

Affiliation Pharmerit International, Bethesda, Maryland, United States of America

Kenneth Johnson

Affiliation Durata Therapeutics, Chicago, Illinois, United States of America

Competing Interests

The authors of this manuscript have read the journal's policy and have the following competing interests: DP, JS, AK, and AP were employees of Pharmerit at time of research and received research funding from Durata. KK was a consultant for Durata. KJ is an employee of Durata and has stock ownership in the company. The authors confirm that this does not alter their adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KK DP JS AK AP KJ. Analyzed the data: DP JS AK AP. Wrote the paper: KK DP JS AK AP KJ.