Machine Learning: How Much Does It Tell about Protein Folding Rates?

Marc Corrales; Pol Cuscó; Dinara R. Usmanova; Heng-Chang Chen; Natalya S. Bogatyreva; Guillaume J. Filion; Dmitry N. Ivankov

doi:10.1371/journal.pone.0143166

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Open Access

Peer-reviewed

Research Article

Machine Learning: How Much Does It Tell about Protein Folding Rates?

Marc Corrales ,

Contributed equally to this work with: Marc Corrales, Pol Cuscó, Dinara R. Usmanova

Affiliations Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Universitat Pompeu Fabra (UPF), Barcelona, Spain, Spain Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain
⨯
Pol Cuscó ,

Contributed equally to this work with: Marc Corrales, Pol Cuscó, Dinara R. Usmanova

Affiliations Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Universitat Pompeu Fabra (UPF), Barcelona, Spain, Spain Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain
⨯
Dinara R. Usmanova ,

Contributed equally to this work with: Marc Corrales, Pol Cuscó, Dinara R. Usmanova

Affiliations Universitat Pompeu Fabra (UPF), Barcelona, Spain, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russia
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Heng-Chang Chen,

Affiliations Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Universitat Pompeu Fabra (UPF), Barcelona, Spain, Spain Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain
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Natalya S. Bogatyreva,

Affiliations Universitat Pompeu Fabra (UPF), Barcelona, Spain, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Laboratory of Protein Physics, Institute of Protein Research of the Russian Academy of Sciences, Pushchino, Moscow Region, Russia
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Guillaume J. Filion,

Affiliations Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Universitat Pompeu Fabra (UPF), Barcelona, Spain, Spain Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain
⨯
Dmitry N. Ivankov

* E-mail: ivankov13@gmail.com

Affiliations Universitat Pompeu Fabra (UPF), Barcelona, Spain, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Laboratory of Protein Physics, Institute of Protein Research of the Russian Academy of Sciences, Pushchino, Moscow Region, Russia
⨯

Machine Learning: How Much Does It Tell about Protein Folding Rates?

Marc Corrales,
Pol Cuscó,
Dinara R. Usmanova,
Heng-Chang Chen,
Natalya S. Bogatyreva,
Guillaume J. Filion,
Dmitry N. Ivankov

Published: November 25, 2015
https://doi.org/10.1371/journal.pone.0143166

About the Authors

Marc Corrales

Contributed equally to this work with: Marc Corrales, Pol Cuscó, Dinara R. Usmanova

Affiliations Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Universitat Pompeu Fabra (UPF), Barcelona, Spain, Spain Genome Architecture, Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain

Pol Cuscó

Contributed equally to this work with: Marc Corrales, Pol Cuscó, Dinara R. Usmanova

Dinara R. Usmanova

Contributed equally to this work with: Marc Corrales, Pol Cuscó, Dinara R. Usmanova

Affiliations Universitat Pompeu Fabra (UPF), Barcelona, Spain, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russia

Heng-Chang Chen

Natalya S. Bogatyreva

Affiliations Universitat Pompeu Fabra (UPF), Barcelona, Spain, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain, Laboratory of Protein Physics, Institute of Protein Research of the Russian Academy of Sciences, Pushchino, Moscow Region, Russia

Guillaume J. Filion

Dmitry N. Ivankov

* E-mail: ivankov13@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Analyzed the data: MC PC DRU HCC NSB GJF DNI. Wrote the paper: GJF DNI.

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Protein folding
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Learning curves
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Machine learning
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Protein structure
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Forecasting
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Linear regression analysis
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Protein structure prediction
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Statistical data
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