About the Authors

Ida Anjomshoaa

Contributed equally to this work with: Ida Anjomshoaa, Jessica Briseño-Ruiz

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Jessica Briseño-Ruiz

Contributed equally to this work with: Ida Anjomshoaa, Jessica Briseño-Ruiz

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Kathleen Deeley

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Fernardo A. Poletta

Affiliation ECLAMC (Latin American Collaborative Study of Congenital Malformations) at CEMIC (Center for Medical Education and Clinical Research), Buenos Aires, Argentina

Juan C. Mereb

Affiliation ECLAMC at Hospital de Area El Bolson, El Bolson, RN, Argentina

Aline L. Leite

Affiliation Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil

Priscila A. T. M. Barreta

Affiliation Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil

Thelma L. Silva

Affiliation Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil

Piper Dizak

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Timothy Ruff

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Asli Patir

Affiliation Department of Pedodontics, Medipol Istanbul University, Istanbul, Turkey

Mine Koruyucu

Affiliation Department of Pedodontics, Istanbul University, Istanbul, Turkey

Zerrin Abbasoğlu

Affiliation Department of Pediatric Dentistry, Yeditepe University, Faculty of Dentistry, Istanbul, Turkey

Priscila L. Casado

Affiliations Dental School, Clinical Research Unit, Federal Fluminense University - UFF, Niterói, RJ, Brazil, Biology Institute, Federal Fluminense University - UFF, Niterói, RJ, Brazil

Andrew Brown

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Samer H. Zaky

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Merve Bayram

Affiliation Department of Pedodontics, Medipol Istanbul University, Istanbul, Turkey

Erika C. Küchler

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Margaret E. Cooper

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Kai Liu

Affiliation Department of Endodontics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Mary L. Marazita

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

İlknur Tanboğa

Affiliation Department of Pediatric Dentistry, Marmara University, Faculty of Dentistry, Istanbul, Turkey

José M. Granjeiro

Affiliations Dental School, Clinical Research Unit, Federal Fluminense University - UFF, Niterói, RJ, Brazil, National Institute of Metrology (INMETRO), Niterói, RJ, Brazil

Figen Seymen

Affiliation Department of Pedodontics, Istanbul University, Istanbul, Turkey

Eduardo E. Castilla

Affiliations ECLAMC (Latin American Collaborative Study of Congenital Malformations) at CEMIC (Center for Medical Education and Clinical Research), Buenos Aires, Argentina, ECLAMC at INAGEMP-CNPq (National Institute of Population Medical Genetics) at Department of Genetics, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

Iêda M. Orioli

Affiliation ECLAMC at INAGEMP-CNPq (National Institute of Population Medical Genetics) at Department of Genetics, Institute of Biology, Center of Health Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil

Charles Sfeir

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Hongjiao Owyang

Affiliation Department of Pediatric Dentistry, Marmara University, Faculty of Dentistry, Istanbul, Turkey

Marília A. R. Buzalaf

Affiliation Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil

Alexandre R. Vieira

arv11@pitt.edu

Affiliation Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ARV IA ECK MLM IT JMG FS EEC IMO CS MARB. Performed the experiments: IA JB-R KD FAP JCM ALL PATMB TLS PLC AB SHZ MB ECK PD TR AP MK ZA KL HO. Analyzed the data: ARV IA JB-R PLC ZA MEC. Contributed reagents/materials/analysis tools: ARV. Wrote the paper: ARV IA JB-R MARB.