About the Authors

Helen R. Stagg

h.stagg@ucl.ac.uk

Affiliation Research Department of Infection and Population Health, University College London, London, United Kingdom

James Brown

Affiliations Centre for Respiratory Medicine, Royal Free London NHS Foundation Trust, London, United Kingdom, Division of Medicine, University College London, London, United Kingdom

Elmira Ibraim

Contributed equally to this work with: Elmira Ibraim, Vija Riekstiņa, Piret Viiklepp

Affiliation Marius Nasta Institute of Pulmonology, Bucharest, Romania

Vija Riekstiņa

Contributed equally to this work with: Elmira Ibraim, Vija Riekstiņa, Piret Viiklepp

Affiliations Centre of TB and Lung Diseases, Riga East University Hospital, Riga, Latvia, University of Latvia, Riga, Latvia

Piret Viiklepp

Contributed equally to this work with: Elmira Ibraim, Vija Riekstiņa, Piret Viiklepp

Affiliation Estonian Tuberculosis Registry, National Institute for Health Development, Tallinn, Estonia

Andra Cīrule

‡ These authors also contributed equally to this work.

Affiliation Centre of TB and Lung Diseases, Riga East University Hospital, Riga, Latvia

Horia Cocei

† Deceased.

‡ These authors also contributed equally to this work.

Affiliation Marius Nasta Institute of Pulmonology, Bucharest, Romania

Manfred Danilovitš

‡ These authors also contributed equally to this work.

Affiliation Lung Clinic, Tartu University Hospital, Tartu, Estonia

Gunta Dravniece

Affiliation KNCV Tuberculosis Foundation, The Hague, The Netherlands

Charlotte Jackson

Affiliation Research Department of Infection and Population Health, University College London, London, United Kingdom

Peter J. White

Affiliations MRC Centre for Outbreak Analysis & Modelling and NIHR Health Protection Research Unit in Modelling Methodology, Department of Infectious Disease Epidemiology, Imperial College School of Public Health, London, United Kingdom, Modelling and Economics Unit, Centre for Infectious Disease Surveillance and Control, Public Health England, London, United Kingdom

Competing Interests

The authors of this manuscript have read the journal's policy and have the following competing interests: Dr. Stagg reports personal fees and other from Otsuka Pharmaceutical, grants from National Institute for Health Research, UK, during the conduct of the study; non-financial support from Sanofi, outside the submitted work. Dr. Brown reports grants and personal fees from Otsuka Pharmaceuticals, during the conduct of the study. Dr. White reports grants and personal fees from Otsuka, during the conduct of the study. Dr. Danilovits reports personal fees and other from Otsuka Pharmaceutical, during the conduct of the study. Dr. Viiklepp reports grants from UCL Consultants Ltd, during the conduct of the study. Dr. Ibraim reports personal fees and non-financial support from Otsuka SA, during the conduct of the study; grants from German Centre for Infection Research- DZIF, outside the submitted work. Dr. Dravniece reports grants and personal fees from Otsuka, during the conduct of the study. Dr. Cocei reports grants from Otsuka SA, during the conduct of the study; grants from Romanian National Tuberculosis Programme, grants from Norway Grants, outside the submitted work. Dr. Jackson reports personal fees from Otsuka Pharmaceutical, grants from National Institute for Health Research, during the conduct of the study. Dr. Riekstina reports personal fees from Otsuka Pharmaceutical (Switzerland) during the conduct of the study. Dr. Cirule has nothing to disclose. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HRS GD PJW. Analyzed the data: HRS JB CJ GD PJW. Contributed reagents/materials/analysis tools: EI VR PV AC HC MD. Wrote the paper: HRS JB EI VR PV AC HC MD GD CJ PJW. Provision of data: EI VR PV AC HC MD.