About the Authors

Kristian H. Mikkelsen

Affiliations Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark, NNF Centre for Basic Metabolic Research and Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Morten Frost

Affiliation Endocrine Research Unit, University of Southern Denmark, Odense, Denmark

Martin I. Bahl

Affiliation National Food Institute, Technical University of Denmark, Søborg, Denmark

Tine R. Licht

Affiliation National Food Institute, Technical University of Denmark, Søborg, Denmark

Ulrich S. Jensen

Affiliation Department of Clinical Microbiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Jacob Rosenberg

Affiliation Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark

Oluf Pedersen

Affiliation NNF Centre for Basic Metabolic Research and Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Torben Hansen

Affiliations NNF Centre for Basic Metabolic Research and Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, Endocrine Research Unit, University of Southern Denmark, Odense, Denmark

Jens F. Rehfeld

Affiliation Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Jens J. Holst

Affiliation NNF Centre for Basic Metabolic Research and Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Tina Vilsbøll

Affiliation Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

Filip K. Knop

filipknop@dadlnet.dk

Affiliations Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark, NNF Centre for Basic Metabolic Research and Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Competing Interests

KM holds shares in Chr. Hansen and Probi. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KHM MF JR OBP TH JJH TV FKK. Performed the experiments: KHM. Analyzed the data: KHM MIB TRL USJ JFR JJH. Contributed reagents/materials/analysis tools: MIB TRL USJ JFR JJH. Wrote the paper: KHM MF MIB TRL USJ JR OP TH JFR JJH TV FKK.