About the Authors

Reynolds K. Brobey

Affiliations Centers for Proteomics and Systems Biology, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston (UTHealth) Medical School, 1825 Pressler Street, Houston, Texas, 77030, United States of America, Division of Oncology, Department of Internal Medicine, The University of Texas Health Science Center at Houston (UTHealth) Medical School, 6410 Fannin, UTPB Suite 722, Houston, Texas 77030 United States of America

Mehdi Dheghani

Affiliations Centers for Proteomics and Systems Biology, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston (UTHealth) Medical School, 1825 Pressler Street, Houston, Texas, 77030, United States of America, Companion Dx Reference Laboratory, LLC, 10301 Stella Link Rd., Suite C, Houston, Texas 77025, United States of America

Philip P. Foster

Affiliations Centers for Proteomics and Systems Biology, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston (UTHealth) Medical School, 1825 Pressler Street, Houston, Texas, 77030, United States of America, Department of NanoMedicine and Biomedical Engineering, The University of Texas Health Science Center at Houston (UTHealth), MD Anderson Cancer Center Bldg-3SCRB, 1881 East Road, Houston, Texas 77030, United States of America, Division of Pulmonary Medicine, Department of Internal Medicine, The University of Texas Health Science Center at Houston (UTHealth) Medical School, 6431 Fannin, MSB 1.274, Houston, Texas 77030, United States of America

Makoto Kuro-o

Affiliations Center for Molecular Medicine, Jichi Medical University, 3311–1 Yakushiji, Shimotsuke, Tochigi 329–0498, JAPAN, Department of Pathology, Center for Mineral Metabolism, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390–9072, United States of America

Kevin P Rosenblatt

Kevin.Rosenblatt@uth.tmc.edu

Affiliations Centers for Proteomics and Systems Biology, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston (UTHealth) Medical School, 1825 Pressler Street, Houston, Texas, 77030, United States of America, Companion Dx Reference Laboratory, LLC, 10301 Stella Link Rd., Suite C, Houston, Texas 77025, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RKB KPR. Performed the experiments: RKB MD. Analyzed the data: RKB KPR PPF. Contributed reagents/materials/analysis tools: MK PPF. Wrote the paper: RKB KPR PPF.