About the Authors

Ayaka Iura

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

Erin Gatenby McNerny

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

Yanshuai Zhang

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

Nobuhiro Kamiya

Current address: Faculty of Budo and Sport Studies, Tenri University, Nara, Japan

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

Margaret Tantillo

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

Michelle Lynch

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

David H. Kohn

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

Yuji Mishina

mishina@umich.edu

Affiliation Department of Biologic & Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AI NK YM. Performed the experiments: AI MT EM. Analyzed the data: AI EM YZ YM ML DK. Contributed reagents/materials/analysis tools: AI NK ML YM. Wrote the paper: AI DK YM. 4-point bending test: MT EM. Study conduct, data collection, data analysis: AI. Data interpretation: AI EM YZ YM ML DK. Drafting manuscript: AI DK YM. Approving final version of manuscript: AI NK EM YZ MT ML DK YM. Responsibility for the integrity of the data analysis: AI YM.