About the Authors

Sebastian Memczak

Contributed equally to this work with: Sebastian Memczak, Panagiotis Papavasileiou

Affiliation Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert Rössle Straße 10, D-13125 Berlin, Germany

Panagiotis Papavasileiou

Contributed equally to this work with: Sebastian Memczak, Panagiotis Papavasileiou

Affiliation Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert Rössle Straße 10, D-13125 Berlin, Germany

Oliver Peters

Affiliation Department of Psychiatry, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, D-12203 Berlin, Germany

Nikolaus Rajewsky

rajewsky@mdc-berlin.de

Affiliation Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert Rössle Straße 10, D-13125 Berlin, Germany

Competing Interests

The authors NR, SM, and PP filed a patent (patent EP15187446) covering the use of blood circular RNAs as biomarkers in neurological diseases. This did not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SM PP NR. Performed the experiments: SM. Analyzed the data: PP SM NR. Contributed reagents/materials/analysis tools: OP. Wrote the paper: SM PP NR.