About the Authors

Xiaobo Guo

Affiliations Department of Statistical Science, School of Mathematics & Computational Science, Sun Yat-Sen University, Guangzhou, GD 510275, China, SYSU-CMU Shunde International Joint Research Institute, Shunde, GD 528300, China, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou, GD 510275, China

Yixi Li

Affiliation Peking University HSBC Business School, Shenzhen, GD 518055, China

Xiaohu Ding

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, GD 510080, China

Mingguang He

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, GD 510080, China

Xueqin Wang

Affiliations Department of Statistical Science, School of Mathematics & Computational Science, Sun Yat-Sen University, Guangzhou, GD 510275, China, SYSU-CMU Shunde International Joint Research Institute, Shunde, GD 528300, China, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou, GD 510275, China, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, GD 510080, China

Heping Zhang

heping.zhang@yale.edu

Affiliations Department of Statistical Science, School of Mathematics & Computational Science, Sun Yat-Sen University, Guangzhou, GD 510275, China, Department of Biostatistics, Yale University School of Public Health, New Haven, CT 06520, United States of America, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou, GD 510275, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XG XW HZ. Performed the experiments: XG. Analyzed the data: XG XW HZ. Contributed reagents/materials/analysis tools: YL XD MH. Wrote the paper: XG YL XD MH XW HZ.