About the Authors

Andrea Pauli

Contributed equally to this work with: Andrea Pauli, Tessa G. Montague

andreapauli77@gmail.com (AP); schier@fas.harvard.edu (AFS)

Affiliation Department of Molecular and Cellular Biology, Harvard University, Cambridge, Masschusetts, United States of America

Tessa G. Montague

Contributed equally to this work with: Andrea Pauli, Tessa G. Montague

Affiliation Department of Molecular and Cellular Biology, Harvard University, Cambridge, Masschusetts, United States of America

Kim A. Lennox

Affiliation Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America

Mark A. Behlke

Affiliation Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America

Alexander F. Schier

andreapauli77@gmail.com (AP); schier@fas.harvard.edu (AFS)

Affiliation Department of Molecular and Cellular Biology, Harvard University, Cambridge, Masschusetts, United States of America

Competing Interests

MAB and KAL are employed by Integrated DNA Technologies, Inc. (IDT), which offers oligonucleotides for sale similar to some of the compounds described in the manuscript. IDT is however not a publicly traded company and the authors personally do not own any shares or equity in IDT. There are no patents or new products in development relating to products described in the present work. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AP AFS. Performed the experiments: AP TGM. Analyzed the data: AP TGM. Contributed reagents/materials/analysis tools: KAL MAB. Wrote the paper: TGM AP AFS. Input for writing the manuscript: MAB.