About the Authors
- Christine Thai
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Affiliation Department of Psychology, Royal Melbourne Institute of Technology, Melbourne, Australia
- Yen Ying Lim
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* E-mail: yen.lim@florey.edu.au
Affiliations The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia, Department of Neurology, Warren Alpert School of Medicine, Brown University, Providence, Rhode Island, United States of America, Department of Neurology, Rhode Island Hospital, Providence, Rhode Island, United States of America
- Victor L. Villemagne
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Affiliations The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia, Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Victoria, Australia, Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
- Simon M. Laws
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Affiliations Centre of Excellence for Alzheimer’s Disease Research and Care, Edith Cowan University, Joondalup, Western Australia, Australia, Sir James McCusker Alzheimer’s Disease Research Unit, Hollywood Private Hospital, Perth, Western Australia, Australia, Co-operative Research Centre for Mental Health, Perth, Western Australia, Australia
- David Ames
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Affiliations Academic Unit for Psychiatry of Old Age, St. Vincent’s Health, The University of Melbourne, Kew, Victoria, Australia, National Ageing Research Institute, Parkville, Victoria, Australia
- Kathryn A. Ellis
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Affiliations The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia, Academic Unit for Psychiatry of Old Age, St. Vincent’s Health, The University of Melbourne, Kew, Victoria, Australia, National Ageing Research Institute, Parkville, Victoria, Australia
- Stephanie R. Rainey-Smith
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Affiliations Centre of Excellence for Alzheimer’s Disease Research and Care, Edith Cowan University, Joondalup, Western Australia, Australia, Sir James McCusker Alzheimer’s Disease Research Unit, Hollywood Private Hospital, Perth, Western Australia, Australia
- Ralph N. Martins
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Affiliations Centre of Excellence for Alzheimer’s Disease Research and Care, Edith Cowan University, Joondalup, Western Australia, Australia, Sir James McCusker Alzheimer’s Disease Research Unit, Hollywood Private Hospital, Perth, Western Australia, Australia
- Colin L. Masters
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Affiliation The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia
- Christopher C. Rowe
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Affiliations Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Victoria, Australia, Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
- Paul Maruff
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Affiliations The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia, Cogstate Ltd., Melbourne, Victoria, Australia
- Australian Imaging, Biomarkers and Lifestyle (AIBL) Research Group
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¶Membership of the Australian Imaging, Biomarkers and Lifestyle (AIBL) Research Group can be found in the Acknowledgments.
Competing Interests
Christine Thai, Yen Ying Lim, Kathryn A. Ellis, Stephanie R. Rainey-Smith and Simon M. Laws report no relevant disclosures. Colin L. Masters is an advisor to Prana Biotechnology Ltd and a consultant to Eli Lilly. R. H. P. is a scientific consultant to Cogstate Ltd. Paul Maruff is a full-time employee of Cogstate Ltd. David Ames has served on scientific advisory boards for Novartis, Eli Lilly, Janssen, and Pfizer Inc. Ralph N. Martins is a consultant to Alzhyme. Christopher C. Rowe has served on scientific advisory boards for Bayer Pharma, Elan Corporation, GE Healthcare and AstraZeneca; has received speaker honoraria from Bayer Pharma and GE Healthcare; and has received research support from Bayer Pharma, GE Healthcare, Piramal Lifesciences and Avid Radiopharmaceuticals. Victor L. Villemagne served as a consultant for Bayer Pharma; and received research support from a NEDO grant from Japan. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: CT YYL PM. Performed the experiments: CT YYL VLV SML. Analyzed the data: CT YYL PM. Contributed reagents/materials/analysis tools: DA RNM CLM PM VLV CCR KAE SRR SML. Wrote the paper: CT YYL PM.