About the Authors

Kristina Hacker

Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Renke Maas

Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Johannes Kornhuber

Affiliation Department of Psychiatry and Psychotherapy, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Martin F. Fromm

Martin.Fromm@fau.de

Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Oliver Zolk

Affiliations Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, Institute of Pharmacology of Natural Products & Clinical Pharmacology, Ulm University, Ulm, Germany

Competing Interests

M.F.F. received personal compensation for expert testimony from Boehringer Ingelheim and payments for lectures from Bayer-Schering Pharma, Boehringer Ingelheim AG, Janssen-Cilag and Sanofi-Aventis Deutschland GmbH. His institution received compensation for commissioned research of his group from Merck KGaA and from Sanofi-Aventis Deutschland GmbH and for supply for in vitro studies from Gilead. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials. The remaining authors (K.H., R.M., J.K., O.Z.) declare no conflicts of interest.

Author Contributions

Conceived and designed the experiments: KH RM JK MFF OZ. Performed the experiments: KH OZ. Analyzed the data: KH OZ. Contributed reagents/materials/analysis tools: JK RM MFF OZ. Wrote the paper: KH MFF OZ.