About the Authors

Asao Noda

asnoda@rerf.or.jp

Affiliation Departments of Genetics, Radiation Effects Research Foundation, 5–2 Hijiyama Park, Minami-ku, Hiroshima, 732–0815, Japan

Hirofumi Suemori

Affiliation Laboratory of Embryonic Stem Cell Research, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara-cho, Shougoin, Sakyo-ku, Kyoto, 606–8507, Japan

Yuko Hirai

Affiliation Departments of Genetics, Radiation Effects Research Foundation, 5–2 Hijiyama Park, Minami-ku, Hiroshima, 732–0815, Japan

Kanya Hamasaki

Affiliation Departments of Genetics, Radiation Effects Research Foundation, 5–2 Hijiyama Park, Minami-ku, Hiroshima, 732–0815, Japan

Yoshiaki Kodama

Affiliation Departments of Genetics, Radiation Effects Research Foundation, 5–2 Hijiyama Park, Minami-ku, Hiroshima, 732–0815, Japan

Hiroshi Mitani

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, 277–8562, Japan

Reid D. Landes

Affiliation Department of Statistics, Radiation Effects Research Foundation, 5–2 Hijiyama Park, Minami-ku, Hiroshima, 732–0815, Japan

Nori Nakamura

Affiliation Departments of Genetics, Radiation Effects Research Foundation, 5–2 Hijiyama Park, Minami-ku, Hiroshima, 732–0815, Japan

Competing Interests

Though a part of this study was supported by Japan Chemical Industry Association, and our Institute, Radiation Effects Research Foundation, patented the mouse strains, the authors have declared that this does not alter the authors' adherence to PLOS policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AN NN. Performed the experiments: AN HS. Analyzed the data: AN RDL NN. Contributed reagents/materials/analysis tools: HS. Wrote the paper: AN RDL NN. Discussion of experimental design: YH KH YK HM.