About the Authors

Yanping Deng

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

Min Yang

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

Feng Xu

Affiliation Shenyang Pharmaceutical University, Wenhua Road #103, Shenyang, 110016, China

Qian Zhang

Affiliation Department of Medicinal Chemistry School of Pharmacy, Fudan University, Shanghai, 200237, China

Qun Zhao

Affiliations State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China, Shenyang Pharmaceutical University, Wenhua Road #103, Shenyang, 110016, China

Haitao Yu

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

Defang Li

Affiliation Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China

Ge Zhang

Affiliation Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China

Aiping Lu

Affiliation Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China

Kenka Cho

Affiliation Takarazuka University of Medical and Health Care, Hanayashiki-Midorigaoka, Takarazuka-city, 6660162, Japan

Fukang Teng

Affiliations State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China, Shenyang Pharmaceutical University, Wenhua Road #103, Shenyang, 110016, China

Peng Wu

Affiliations State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China, Shenyang Pharmaceutical University, Wenhua Road #103, Shenyang, 110016, China

Linlin Wang

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

Wanying Wu

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

Xuan Liu

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

De-an Guo

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

Baohong Jiang

jiangbh@simm.ac.cn

Affiliation State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BJ. Performed the experiments: YD Q. Zhao HY PW FT DL MY. Analyzed the data: GZ KC Q. Zhang FX LW. Contributed reagents/materials/analysis tools: WW XL. Wrote the paper: DG AL.