Cell Surface Expression Level Variation between Two Common Human Leukocyte Antigen Alleles, HLA-A2 and HLA-B8, Is Dependent on the Structure of the C Terminal Part of the Alpha 2 and the Alpha 3 Domains

Christoffer Dellgren; Jan O. Nehlin; Torben Barington

doi:10.1371/journal.pone.0135385

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Peer-reviewed

Research Article

Cell Surface Expression Level Variation between Two Common Human Leukocyte Antigen Alleles, HLA-A2 and HLA-B8, Is Dependent on the Structure of the C Terminal Part of the Alpha 2 and the Alpha 3 Domains

Christoffer Dellgren,

Affiliation Department of Clinical Immunology, Odense University Hospital, Odense, Denmark
⨯
Jan O. Nehlin,

Affiliation Department of Clinical Immunology, Odense University Hospital, Odense, Denmark
⨯
Torben Barington

* E-mail: barington@dadlnet.dk

Affiliation Department of Clinical Immunology, Odense University Hospital, Odense, Denmark
⨯

Cell Surface Expression Level Variation between Two Common Human Leukocyte Antigen Alleles, HLA-A2 and HLA-B8, Is Dependent on the Structure of the C Terminal Part of the Alpha 2 and the Alpha 3 Domains

Christoffer Dellgren,
Jan O. Nehlin,
Torben Barington

Published: August 10, 2015
https://doi.org/10.1371/journal.pone.0135385

About the Authors

Christoffer Dellgren

Affiliation Department of Clinical Immunology, Odense University Hospital, Odense, Denmark

Jan O. Nehlin

Affiliation Department of Clinical Immunology, Odense University Hospital, Odense, Denmark

Torben Barington

* E-mail: barington@dadlnet.dk

Affiliation Department of Clinical Immunology, Odense University Hospital, Odense, Denmark

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CD JN TB. Performed the experiments: CD. Analyzed the data: CD JN TB. Contributed reagents/materials/analysis tools: JN TB. Wrote the paper: CD JN TB.

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Messenger RNA
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Gene expression
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