About the Authors

Marian C. Aldhous

M.Aldhous@ed.ac.uk

Affiliation Tommy’s Centre for Maternal and Fetal Health, MRC Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Rebecca M. Reynolds

Affiliation Endocrinology Unit, University/BHF Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Archie Campbell

Affiliation Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Pamela Linksted

Affiliation Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Robert S. Lindsay

Affiliation British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom

Blair H. Smith

Affiliation Medical Research Institute, University of Dundee, Dundee, United Kingdom

Jonathan R. Seckl

Affiliation Endocrinology Unit, University/BHF Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

David J. Porteous

Affiliations Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom, Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Jane E. Norman

Affiliation Tommy’s Centre for Maternal and Fetal Health, MRC Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Generation Scotland

Membership of Generation Scotland is listed in the Acknowledgments.

Affiliations Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom, Generation Scotland: A Collaboration between the University Medical Schools and NHS in Aberdeen, Dundee, Edinburgh and Glasgow, Scotland, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JEN RMR RSL BHS DJP JRS. Performed the experiments: MCA AC. Analyzed the data: MCA. Contributed reagents/materials/analysis tools: AC PL. Wrote the paper: MCA JEN RMR RSL BHS DJP JRS. Obtained permissions on behalf of Generation Scotland: PL. Obtained permissions for the research: MCA.