About the Authors

John A. Gaynes

Affiliations Program in Neuroscience, University of Utah Medical Center, Salt Lake City, Utah, United States of America, Department of Neurobiology and Anatomy, University of Utah Medical Center, Salt Lake City, Utah, United States of America, Department of Ophthalmology/Visual Sciences, John A. Moran Center, University of Utah Medical Center, Salt Lake City, Utah, United States of America

Hideo Otsuna

Affiliation Department of Neurobiology and Anatomy, University of Utah Medical Center, Salt Lake City, Utah, United States of America

Douglas S. Campbell

Affiliations Department of Neurobiology and Anatomy, University of Utah Medical Center, Salt Lake City, Utah, United States of America, Max Planck Institute for Brain Research, Frankfurt am Main, Germany

John P. Manfredi

Affiliation Sfida BioLogic, Inc., Salt Lake City, Utah, United States of America

Edward M. Levine

ed.levine@utah.edu

Affiliations Program in Neuroscience, University of Utah Medical Center, Salt Lake City, Utah, United States of America, Department of Neurobiology and Anatomy, University of Utah Medical Center, Salt Lake City, Utah, United States of America, Department of Ophthalmology/Visual Sciences, John A. Moran Center, University of Utah Medical Center, Salt Lake City, Utah, United States of America

Chi-Bin Chien

† Deceased.

Affiliations Program in Neuroscience, University of Utah Medical Center, Salt Lake City, Utah, United States of America, Department of Neurobiology and Anatomy, University of Utah Medical Center, Salt Lake City, Utah, United States of America

Competing Interests

JM, Chief Scientific Officer of Sfidia BioLogic, served as a visiting faculty scientist in CBC’s lab and provided intellectual contribution to the quantification of the Kaede timelapse experiment in Fig 1 of this manuscript. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials, including but not limited to Sfidia BioLogic’s employment, consultancy, patents, or products in development or marketing.

Author Contributions

Conceived and designed the experiments: JG EL CBC. Performed the experiments: JG. Analyzed the data: JG HO JM EL CBC. Contributed reagents/materials/analysis tools: JG HO DC EL CBC. Wrote the paper: JG HO DC JM EL.