About the Authors

Moon Young Lee

Affiliations Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America, Department of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do, Korea

Chanjae Park

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Robyn M. Berent

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Paul J. Park

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Robert Fuchs

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Hannah Syn

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Albert Chin

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Jared Townsend

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Craig C. Benson

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

Doug Redelman

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Tsai-wei Shen

Affiliation LC Sciences, 2575 West Bellfort Street Suite 270, Houston, Texas, United States of America

Jong Kun Park

Affiliation Division of Biological Science, Wonkwang University, Iksan, Jeollabuk-do, South Korea

Joseph M. Miano

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

Kenton M. Sanders

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Seungil Ro

sro@medicine.nevada.edu

Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

Competing Interests

T. Shen is an employee of LC Sciences. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MYL CP SR. Performed the experiments: MYL CP RB PJP RF JT. Analyzed the data: MYL HS AC CCB JPK TWS DR SR. Contributed reagents/materials/analysis tools: JMM KMS. Wrote the paper: JMM KMS SR.