About the Authors

Stefan Huber

Affiliation Pharmaceutical and Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany

Johannes Philip Huettner

Affiliation Pharmacology and Toxicology, Institute of Pharmacy, University of Regensburg, Regensburg, Germany

Kristina Hacker

Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Günther Bernhardt

Affiliation Pharmaceutical and Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany

Jörg König

Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Armin Buschauer

armin.buschauer@chemie.uni-regensburg.de

Affiliation Pharmaceutical and Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany

Competing Interests

This work was in part supported by Arevipharma (Radebeul, Germany). This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SH GB JK AB. Performed the experiments: SH JPH KH. Analyzed the data: SH GB JK AB. Contributed reagents/materials/analysis tools: JPH KH JK. Wrote the paper: SH JPH GB JK AB.