Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels

Carolina Thörn Pérez; Russell H. Hill; Sten Grillner

doi:10.1371/journal.pone.0133136

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Open Access

Peer-reviewed

Research Article

Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels

Carolina Thörn Pérez,

Affiliation Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
⨯
Russell H. Hill,

Affiliation Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
⨯
Sten Grillner

* E-mail: sten.grillner@ki.se

Affiliation Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
⨯

Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels

Carolina Thörn Pérez,
Russell H. Hill,
Sten Grillner

Published: July 21, 2015
https://doi.org/10.1371/journal.pone.0133136

About the Authors

Carolina Thörn Pérez

Affiliation Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

Russell H. Hill

Affiliation Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

Sten Grillner

* E-mail: sten.grillner@ki.se

Affiliation Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CTP SG RH. Performed the experiments: CTP. Analyzed the data: CTP RH. Contributed reagents/materials/analysis tools: SG. Wrote the paper: CTP RH SG.

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Membrane potential
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Potassium channels
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Depolarization
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Spinal cord
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Neurons
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Lampreys
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Endocannabinoids
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Mammals
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