About the Authors

Virginie Dutoit-Lefèvre

Contributed equally to this work with: Virginie Dutoit-Lefèvre, Sylvain Dubucquoi

virginiedutoitlefevre@gmail.com

Affiliations Institut d’Immunologie, Centre de Biologie Pathologie et Génétique, Centre Hospitalier Régional Universitaire, Lille, France, UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France

Sylvain Dubucquoi

Contributed equally to this work with: Virginie Dutoit-Lefèvre, Sylvain Dubucquoi

Affiliations Institut d’Immunologie, Centre de Biologie Pathologie et Génétique, Centre Hospitalier Régional Universitaire, Lille, France, UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France

David Launay

Affiliations UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France, Service de Médecine Interne et d’Immunologie clinique, Centre National de Référence Maladies rares, Centre Hospitalier Régional Universitaire, Lille, France

Vincent Sobanski

Affiliations UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France, Service de Médecine Interne et d’Immunologie clinique, Centre National de Référence Maladies rares, Centre Hospitalier Régional Universitaire, Lille, France

Patricia Dussart

Affiliations Institut d’Immunologie, Centre de Biologie Pathologie et Génétique, Centre Hospitalier Régional Universitaire, Lille, France, UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France

Philippe Chafey

Affiliations INSERM U1016, Institut Cochin, Paris, France, UMR 8104, CNRS Paris, France, Plate-forme Protéomique 3P5, Univ Paris Descartes, Sorbonne Paris Cité, Paris, France

Cédric Broussard

Affiliations INSERM U1016, Institut Cochin, Paris, France, UMR 8104, CNRS Paris, France, Plate-forme Protéomique 3P5, Univ Paris Descartes, Sorbonne Paris Cité, Paris, France

Sophie Duban-Deweer

Affiliations EA 2686, Univ Lille Nord de France, Lille, France, LBHE, EA 2465, UArtois, Lens, France

Patrick Vermersch

Affiliations UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France, Service de Neurologie D, Centre Hospitalier Régional Universitaire, Lille, France

Lionel Prin

Affiliations Institut d’Immunologie, Centre de Biologie Pathologie et Génétique, Centre Hospitalier Régional Universitaire, Lille, France, UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France

Didier Lefranc

Affiliations UMR 995, LIRIC, INSERM, Lille, France, EA 2686, Univ Lille Nord de France, Lille, France

Competing Interests

Pfizer and Merck Serono provided funding towards this study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: VDL SD DLa DLe. Performed the experiments: VDL VS PD CB SDD DLe. Analyzed the data: VDL VS SD DLa CB DLe. Contributed reagents/materials/analysis tools: VDL PD PC CB SDD DLe. Wrote the paper: VDL SD DLa PD PC CB SDD PV LP DLe.