About the Authors

Lei Li

Affiliation Vaxine Pty Ltd, Flinders Medical Centre, Bedford Park, Adelaide, Australia

Yoshikazu Honda-Okubo

Affiliation Vaxine Pty Ltd, Flinders Medical Centre, Bedford Park, Adelaide, Australia

Connie Li

Affiliation Vaxine Pty Ltd, Flinders Medical Centre, Bedford Park, Adelaide, Australia

Dimitar Sajkov

Affiliation Australian Respiratory and Sleep Medicine Institute, Flinders Medical Centre, Bedford Park, Adelaide, Australia

Nikolai Petrovsky

nikolai.petrovsky@flinders.edu.au

Affiliations Vaxine Pty Ltd, Flinders Medical Centre, Bedford Park, Adelaide, Australia, Department of Endocrinology, Flinders Medical Centre/Flinders University, Adelaide, Australia

Competing Interests

LL, YHO, CL and NP are employees of Vaxine Pty Ltd, which has interests in Advax adjuvant. Vaxine Pty Ltd was the trial sponsor for FLU006-­‐12. Vaxine Pty Ltd holds the following patents relating to material pertinent to this study: (Family of International (PCT) Patent Application No. PCT/AU2005/001328 entitled New polymorphic form of inulin and uses thereof and Family of International (PCT) Patent Application No. PCT/EP2012/061748 entitled Enhanced immunological composition). There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LL DS NP. Performed the experiments: LL YHO CL. Analyzed the data: LL NP. Wrote the paper: LL NP. Clinical Trial Investigator: DS.