About the Authors

Yumie Morimoto-Kobayashi

Yumie_Kobayashi@kirin.co.jp

Affiliation Research Laboratories for Health Science & Food Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Kazuaki Ohara

Affiliation Research Laboratories for Health Science & Food Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Chika Takahashi

Affiliation Research Laboratories for Health Science & Food Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Sayoko Kitao

Affiliation Research Laboratories for Health Science & Food Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Guanying Wang

Affiliation Research Laboratories for Health Science & Food Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Yoshimasa Taniguchi

Current address: Central Laboratories for Key Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Affiliation Research Laboratories for Health Science & Food Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Mikio Katayama

Affiliation Research Laboratories for Health Science & Food Technologies, KIRIN Company, Ltd., Yokohama, Kanagawa, Japan

Katsuya Nagai

Affiliation ANBAS Corporation, Osaka, Japan

Competing Interests

YMK, KO, CT, SK, GW, YT & MK are employees of Kirin Company, Ltd. KN is the President of ANBAS Corporation. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YMK KO MK KN. Performed the experiments: YMK CT SK GW YT KN. Analyzed the data: YMK CT SK GW YT KN. Contributed reagents/materials/analysis tools: YT. Wrote the paper: YMK KO MK KN.