About the Authors

Claudia Vollbrecht

Affiliations Institute of Pathology, University Hospital Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Center of Molecular Medicine Cologne, University of Cologne, Cologne, Germany

Fabian Dominik Mairinger

Affiliation Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Ulrike Koitzsch

Affiliations Institute of Pathology, University Hospital Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Center of Molecular Medicine Cologne, University of Cologne, Cologne, Germany

Martin Peifer

Affiliations Center of Molecular Medicine Cologne, University of Cologne, Cologne, Germany, Department of Translational Genomics, Cologne Center of Genomics, University of Cologne, Cologne, Germany

Katharina Koenig

Affiliations Institute of Pathology, University Hospital Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Center of Molecular Medicine Cologne, University of Cologne, Cologne, Germany

Lukas Carl Heukamp

Current address: Institute for Hematopathology Hamburg, Hamburg, Germany; New Oncology, Cologne, Germany

Affiliations Institute of Pathology, University Hospital Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany

Giuliano Crispatzu

Affiliations Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany

Laura Wilden

Affiliations Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany

Karl-Anton Kreuzer

Affiliations Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany

Michael Hallek

Affiliations Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany

Margarete Odenthal

Contributed equally to this work with: Margarete Odenthal, Carmen Diana Herling, Reinhard Buettner

Affiliations Institute of Pathology, University Hospital Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Center of Molecular Medicine Cologne, University of Cologne, Cologne, Germany

Carmen Diana Herling

Contributed equally to this work with: Margarete Odenthal, Carmen Diana Herling, Reinhard Buettner

reinhard.buettner@uk-koeln.de (RB); carmen.herling@uk-koeln.de (CDH)

Affiliations Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany

Reinhard Buettner

Contributed equally to this work with: Margarete Odenthal, Carmen Diana Herling, Reinhard Buettner

reinhard.buettner@uk-koeln.de (RB); carmen.herling@uk-koeln.de (CDH)

Affiliations Institute of Pathology, University Hospital Cologne, Cologne, Germany, Center for Integrated Oncology (CIO) Cologne-Bonn, University Hospital Cologne, Cologne, Germany, Center of Molecular Medicine Cologne, University of Cologne, Cologne, Germany

Competing Interests

The authors have declared that no competing interest exist.

Author Contributions

Conceived and designed the experiments: CV CDH MO KK. Performed the experiments: CV LW UK. Analyzed the data: CV FDM GC CDH MO. Contributed reagents/materials/analysis tools: MO CDH KAK MH MP LCH. Wrote the paper: CV MO CDH RB.