About the Authors

Hiroyuki Tamiya

Affiliation Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Hideo Yasunaga

Affiliation Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan

Hiroki Matusi

Affiliation Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan

Kiyohide Fushimi

Affiliation Department of Health Policy and Informatics, Tokyo Medical and Dental University Graduate School of Medicine, Tokyo, Japan

Sumito Ogawa

suogawa-tky@umin.ac.jp

Affiliation Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Masahiro Akishita

Affiliation Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Competing Interests

The authors have read the journal's policy and have the following competing interests: MA received research grant support by Daiichi-Sankyo and Takeda, and honoraria for educational lectures by Daiichi-Sankyo Takeda, Eisai, Novartis and Mochida. SO received honoraria for educational lectures by Abbott and Daiichi-Sankyo. Other authors declare no conflict of interest. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HT HY SO. Performed the experiments: HT HY SO. Analyzed the data: HT HY SO. Contributed reagents/materials/analysis tools: HM KF HY. Wrote the paper: HT HY MA SO.