About the Authors

Haruhiko Tokuda

tokuda@ncgg.go.jp

Affiliations Department of Clinical Laboratory, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan, Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

Gen Kuroyanagi

Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

Masanori Tsujimoto

Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan

Yukiko Enomoto

Affiliation Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan

Rie Matsushima-Nishiwaki

Affiliation Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

Takashi Onuma

Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

Akiko Kojima

Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Anesthesiology and Critical Care Medicine, Matsunami General Hospital, Gifu, Japan

Tomoaki Doi

Affiliation Department of Emergency and Disaster Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

Kumiko Tanabe

Affiliation Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

Shigeru Akamatsu

Affiliation Department of Anesthesiology and Critical Care Medicine, Matsunami General Hospital, Gifu, Japan

Hiroki Iida

Affiliation Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

Shinji Ogura

Affiliation Department of Emergency and Disaster Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

Takanobu Otsuka

Affiliation Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

Toru Iwama

Affiliation Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan

Takahisa Tanikawa

Affiliation Department of Clinical Laboratory, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Kei Ishikawa

Affiliation Department of Clinical Laboratory, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Kumi Kojima

Affiliation Department of Clinical Laboratory, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Osamu Kozawa

Affiliation Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HT OK. Performed the experiments: HT GK MT TT T. Onuma AK KI. Analyzed the data: HT RM-N TD KT KK OK. Wrote the paper: HT YE SA HI SO T. Otsuka TI OK.