Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics

Sasha J. Rose; Lmar M. Babrak; Luiz E. Bermudez

doi:10.1371/journal.pone.0128772

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Peer-reviewed

Research Article

Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics

Sasha J. Rose,

Affiliations Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, United States of America, Department of Microbiology, College of Science, Oregon State University, Corvallis, Oregon, United States of America
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Lmar M. Babrak,

Affiliations Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, United States of America, Department of Microbiology, College of Science, Oregon State University, Corvallis, Oregon, United States of America
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Luiz E. Bermudez

* E-mail: Luiz.Bermudez@oregonstate.edu

Affiliations Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, United States of America, Department of Microbiology, College of Science, Oregon State University, Corvallis, Oregon, United States of America
⨯

Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics

Sasha J. Rose,
Lmar M. Babrak,
Luiz E. Bermudez

Published: May 26, 2015
https://doi.org/10.1371/journal.pone.0128772

About the Authors

Sasha J. Rose

Affiliations Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, United States of America, Department of Microbiology, College of Science, Oregon State University, Corvallis, Oregon, United States of America

Lmar M. Babrak

Luiz E. Bermudez

* E-mail: Luiz.Bermudez@oregonstate.edu

Competing Interests

The authors has declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SR LEB. Performed the experiments: SR LB. Analyzed the data: SR LEB. Contributed reagents/materials/analysis tools: SR LB LEB. Wrote the paper: SR LEB.

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Bacterial biofilms
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Deoxyribonucleases
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Mycobacterium avium complex
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Genomics
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Lysis (medicine)
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Biofilms
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Random amplified polymorphic DNA technique
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Nontuberculous mycobacteria
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