About the Authors

Antonio Di Grazia

Affiliation Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy

Floriana Cappiello

Affiliation Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy

Akiko Imanishi

Affiliation Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom

Arianna Mastrofrancesco

Affiliation Laboratory of Cutaneous Physiopathology and Integrated Center of Metabolomics Research, San Gallicano Dermatologic Institute, Rome, Italy

Mauro Picardo

Affiliation Laboratory of Cutaneous Physiopathology and Integrated Center of Metabolomics Research, San Gallicano Dermatologic Institute, Rome, Italy

Ralf Paus

Affiliations Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, Department of Dermatology, University of Münster, Münster, Germany

Maria Luisa Mangoni

marialuisa.mangoni@uniroma1.it

Affiliation Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy

Competing Interests

The authors of this manuscript have the following competing interests: Part of the content of this work is the object of a pending US patent application n. 14/506,383 (belonging to Houston and Sapienza Universities). Title of Invention: Esculentin 1a Derivatives and Uses Thereof. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MLM ADG. Performed the experiments: ADG FC AI AM. Analyzed the data: ADG MLM. Contributed reagents/materials/analysis tools: MLM MP RP. Wrote the paper: MLM RP.