About the Authors

Hanneke Hoelen

Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

Arnaud Zaldumbide

Affiliation Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

Wouter F. van Leeuwen

Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

Ellen C. W. Torfs

Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

Marten A. Engelse

Affiliation Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands

Chopie Hassan

Affiliation Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

Robert Jan Lebbink

Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

Eelco J. de Koning

Affiliation Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands

Maaike E. Resssing

Affiliations Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

Arnoud H. de Ru

Affiliation Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

Peter A. van Veelen

Affiliation Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

Rob C. Hoeben

Affiliation Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

Bart O. Roep

Affiliation Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

Emmanuel J. H. J. Wiertz

e.wiertz@umcutrecht.nl

Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

Competing Interests

The authors acknowledge Dr. Yihong Ye for the Derlin-1 expression construct. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HH BR EW. Performed the experiments: HH AZ WvL ET CH AR. Analyzed the data: HH AZ PvV EW. Contributed reagents/materials/analysis tools: ME RJL EK CH AR PvV. Wrote the paper: HH AZ MR RH BR EW.