Inhibition of a Putative Dihydropyrimidinase from Pseudomonas aeruginosa PAO1 by Flavonoids and Substrates of Cyclic Amidohydrolases

Cheng-Yang Huang

doi:10.1371/journal.pone.0127634

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Peer-reviewed

Research Article

Inhibition of a Putative Dihydropyrimidinase from Pseudomonas aeruginosa PAO1 by Flavonoids and Substrates of Cyclic Amidohydrolases

Cheng-Yang Huang

* E-mail: cyhuang@csmu.edu.tw

Affiliations School of Biomedical Sciences, Chung Shan Medical University, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan, Department of Medical Research, Chung Shan Medical University Hospital, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan
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Inhibition of a Putative Dihydropyrimidinase from Pseudomonas aeruginosa PAO1 by Flavonoids and Substrates of Cyclic Amidohydrolases

Cheng-Yang Huang

Published: May 19, 2015
https://doi.org/10.1371/journal.pone.0127634

About the Authors

Cheng-Yang Huang

* E-mail: cyhuang@csmu.edu.tw

Affiliations School of Biomedical Sciences, Chung Shan Medical University, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan, Department of Medical Research, Chung Shan Medical University Hospital, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan

Competing Interests

This author has no support or funding to report.

Author Contributions

Conceived and designed the experiments: CYH. Performed the experiments: CYH. Analyzed the data: CYH. Contributed reagents/materials/analysis tools: CYH. Wrote the paper: CYH.

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Pseudomonas aeruginosa
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Crystal structure
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Fluorescence
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Competitive inhibitors
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Emission spectra
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Enzyme inhibitors
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Sequence alignment
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Hydrolysis
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