About the Authors

Silvia Carreira Ribeiro

Affiliation School of Medicine, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Brazil

Ana Elizabeth Figueiredo

Affiliation Graduate Program in Medicine and Health Sciences, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil

Pasqual Barretti

Affiliation School of Medicine, UNESP, Botucatu, Brazil

Roberto Pecoits-Filho

Affiliation School of Medicine, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Brazil

Thyago Proenca de Moraes

thyago.moraes@pucpr.br

Affiliation School of Medicine, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Brazil

all centers that contributed to the BRAZPD II study

Centers that contributed to the BRAZPD II are provided in the Acknowledgments.

Competing Interests

AF has received consulting fees and a speaker honorarium from Baxter Healthcare. PB has received consulting fees and a speaker honorarium from Baxter Healthcare. RPF has received research grants, consulting fees and speaker honorarium from Baxter Healthcare. TPM has received consulting fees and speaker honorarium from Baxter Healthcare. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SCR RPF TPM. Performed the experiments: SCR AEF PB RPF TPM. Analyzed the data: SCR TPM. Contributed reagents/materials/analysis tools: SCR AEF PB RPF TPM. Wrote the paper: SCR AEF PB RPF TPM.