About the Authors
- Florry E. van den Boogaard
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* E-mail: f.e.vandenboogaard@amc.uva.nl
Affiliations Laboratory of Experimental Intensive Care and Anesthesiology (L·E·I·C·A), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
- Jorrit J. Hofstra
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Affiliation Laboratory of Experimental Intensive Care and Anesthesiology (L·E·I·C·A), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
- Cornelis van ‘t Veer
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Affiliations Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
- Marcel M. Levi
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Affiliation Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
- Joris J. T. H. Roelofs
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Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
- Tom van der Poll
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Affiliations Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
- Marcus J. Schultz
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Affiliations Laboratory of Experimental Intensive Care and Anesthesiology (L·E·I·C·A), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Competing Interests
Novartis donated an unrestricted grant to the Academic Medical Center Amsterdam, and supplied Tifacogin (recombinant human TFPI) for the experiments. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: FvdB JJH CvtV TvdP MJS. Performed the experiments: FvdB JJH. Analyzed the data: FvdB JJTHR. Contributed reagents/materials/analysis tools: MML. Wrote the paper: FvdB MJS.