About the Authors

Hideaki Sueoka

Affiliation Genomic Science Laboratories, Sumitomo Dainippon Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554–0022, Japan

Junji Ichihara

Affiliation Drug Development Research Laboratories, Sumitomo Dainippon Pharma Co., Ltd., 33–94 Enokicho, Suita, Osaka 564–0053, Japan

Takahiro Tsukimura

Affiliation Department of Functional Bioanalysis, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204–8588, Japan

Tadayasu Togawa

Affiliation Department of Functional Bioanalysis, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204–8588, Japan

Hitoshi Sakuraba

sakuraba@my-pharm.ac.jp

Affiliation Department of Clinical Genetics, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204–8588, Japan

Competing Interests

Although the study received funding from a commercial source (Sumitomo Dainippon Pharma Co., Ltd.), this funding was solely for research activity, and was not used for employment, consultancy, patents, products in development, or marketed products related to commercial sources. Although H. Sueoka and J. Ichihara are employees of Sumitomo Dainippon Pharma Co., Ltd., they have no competing interest. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials. All authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: H. Sueoka JI T. Tsukimura T. Togawa H. Sakuraba. Performed the experiments: H. Sueoka JI. Analyzed the data: H. Sueoka JI H. Sakuraba. Contributed reagents/materials/analysis tools: H. Sueoka JI T. Tsukimura T. Togawa H. Sakuraba. Wrote the paper: H. Sueoka JI T. Tsukimura T. Togawa H. Sakuraba.