Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome

Hwa-Young Sun; Nari Kim; Cheol-Sang Hwang; Joo-Yeon Yoo

doi:10.1371/journal.pone.0125599

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Open Access

Peer-reviewed

Research Article

Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome

Hwa-Young Sun,

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea
⨯
Nari Kim,

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea
⨯
Cheol-Sang Hwang,

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea
⨯
Joo-Yeon Yoo

* E-mail: jyoo@postech.ac.kr

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea
⨯

Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome

Hwa-Young Sun,
Nari Kim,
Cheol-Sang Hwang,
Joo-Yeon Yoo

Published: May 1, 2015
https://doi.org/10.1371/journal.pone.0125599

About the Authors

Hwa-Young Sun

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea

Nari Kim

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea

Cheol-Sang Hwang

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea

Joo-Yeon Yoo

* E-mail: jyoo@postech.ac.kr

Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HYS NK JYY. Performed the experiments: HYS NK. Analyzed the data: HYS JYY. Contributed reagents/materials/analysis tools: CSH. Wrote the paper: HYS JYY.

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Chromatin
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Small interfering RNA
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Immunoprecipitation
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Proteasomes
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Transfection
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Ubiquitination
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Immunoblotting
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Histones
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