About the Authors
- Ka-Man Venus Lai
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Guochun Gong
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Amanda Atanasio
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- José Rojas
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Joseph Quispe
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Julita Posca
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Derek White
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Mei Huang
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Daria Fedorova
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Craig Grant
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Lawrence Miloscio
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Gustavo Droguett
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- William T. Poueymirou
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- Wojtek Auerbach
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- George D. Yancopoulos
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- David Frendewey
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Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
- John Rinn
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* E-mail: david.valenzuela@regeneron.com (DV); john_rinn@harvard.edu (JR)
Affiliations Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
- David M. Valenzuela
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* E-mail: david.valenzuela@regeneron.com (DV); john_rinn@harvard.edu (JR)
Affiliation VelociGene, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, United States of America
Competing Interests
K-MVL, GG, AA, J. Rojas, JQ, JP, DW, MH, D. Fedorova, CG, LM, GD, WTP, WA, GDY, DF, DMV are employees of VelociGene, Regeneron Pharmaceuticals, Inc. A patent application has been filed relating to this work, title: LincRNA-deficient non-human animals and application No: US 14/454,464 and PCT/US2014/050178. There is no product in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: K-MVL WA D. Frendewey GDY J. Rinn DMV. Performed the experiments: GG AA J. Rojas JQ JP DW MH D. Fedorova CG LM GD WTP. Analyzed the data: K-MVL GG AA J. Rojas JQ JP DW MH D. Fedorova CG LM GD WTP WA D. Frendewey DMV. Wrote the paper: K-MVL GG D. Frendewey DMV.