About the Authors

Christine How

Affiliations Ontario Cancer Institute, University Health Network, Toronto, ON, Canada, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

Melania Pintilie

Affiliation Division of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

Jeff P. Bruce

Affiliations Ontario Cancer Institute, University Health Network, Toronto, ON, Canada, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

Angela B. Y. Hui

Affiliation Ontario Cancer Institute, University Health Network, Toronto, ON, Canada

Blaise A. Clarke

Affiliation Department of Pathology, University Health Network, Toronto, ON, Canada

Philip Wong

Affiliations Ontario Cancer Institute, University Health Network, Toronto, ON, Canada, Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada

Shaoming Yin

Affiliation Informatics & Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, ON, Canada

Rui Yan

Affiliation Informatics & Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, ON, Canada

Daryl Waggott

Affiliation Informatics & Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, ON, Canada

Paul C. Boutros

Affiliations Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, Informatics & Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, ON, Canada, Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada

Anthony Fyles

Affiliations Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada

David W. Hedley

Affiliations Ontario Cancer Institute, University Health Network, Toronto, ON, Canada, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, Division of Medical Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

Richard P. Hill

Affiliations Ontario Cancer Institute, University Health Network, Toronto, ON, Canada, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

Michael Milosevic

Affiliations Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada

Fei-Fei Liu

Fei-Fei.Liu@rmp.uhn.on.ca

Affiliations Ontario Cancer Institute, University Health Network, Toronto, ON, Canada, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CH FFL ABYH. Performed the experiments: CH. Analyzed the data: JPB MP PW SY RY. Contributed reagents/materials/analysis tools: DW PCB RPH DH MM AF BAC FFL. Wrote the paper: CH.