About the Authors

Eriko Simamura

Affiliation Department of Anatomy, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Tomohiro Arikawa

Affiliation Department of Biology, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Takayuki Ikeda

Affiliation Department of Biochemistry, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Hiroki Shimada

Affiliation Department of Anatomy, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Hiroki Shoji

Affiliation Department of Biology, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Hiroko Masuta

Affiliation Department of Anatomy, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Yuriko Nakajima

Affiliation Department of Anatomy, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Hiroki Otani

Affiliation Department of Developmental Biology, Faculty of Medicine, Shimane University, Izumo 693–8601, Japan

Hideto Yonekura

Affiliation Department of Biochemistry, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Toshihisa Hatta

thatta@kanazawa-med.ac.jp

Affiliation Department of Anatomy, Kanazawa Medical University School of Medicine, Uchinada, Ishikawa 920–0293, Japan

Competing Interests

The authors have read the journal’s policy and have the following conflicts. Kanazawa Medical University has filed patent applications on aspects of this work. E. Simamura, H Shimada, T Hatta are named as inventors with Kanazawa Medical University on patent application number PCT/JP2010001217 (patent name: Method for enucleating nucleated erythrocyte, and enucleation inducer). This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ES TA TH. Performed the experiments: ES TA TI H. Shimada H. Shoji HM YN. Analyzed the data: ES TA H. Shimada H. Shoji HY TH. Contributed reagents/materials/analysis tools: ES TA TI H. Shimada H. Shoji HM YN. Wrote the paper: ES TA HO TH.