S-Adenosyl-L-Methionine for the Treatment of Chronic Liver Disease: A Systematic Review and Meta-Analysis

Tao Guo; Lei Chang; Yusha Xiao; Quanyan Liu

doi:10.1371/journal.pone.0122124

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Open Access

Peer-reviewed

Research Article

S-Adenosyl-L-Methionine for the Treatment of Chronic Liver Disease: A Systematic Review and Meta-Analysis

Tao Guo ,

Contributed equally to this work with: Tao Guo, Lei Chang

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China
⨯
Lei Chang ,

Contributed equally to this work with: Tao Guo, Lei Chang

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China
⨯
Yusha Xiao,

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China
⨯
Quanyan Liu

* E-mail: lqy@whu.edu.cn

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China
⨯

S-Adenosyl-L-Methionine for the Treatment of Chronic Liver Disease: A Systematic Review and Meta-Analysis

Tao Guo,
Lei Chang,
Yusha Xiao,
Quanyan Liu

Published: March 16, 2015
https://doi.org/10.1371/journal.pone.0122124

About the Authors

Tao Guo

Contributed equally to this work with: Tao Guo, Lei Chang

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China

Lei Chang

Contributed equally to this work with: Tao Guo, Lei Chang

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China

Yusha Xiao

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China

Quanyan Liu

* E-mail: lqy@whu.edu.cn

Affiliation Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, P.R. China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: QL TG. Performed the experiments: TG LC YX. Analyzed the data: TG LC YX. Contributed reagents/materials/analysis tools: TG. Wrote the paper: QL TG.

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Drug therapy
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Adverse events
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Chronic liver disease
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Liver diseases
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Metaanalysis
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Pruritus
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Alcoholic liver disease
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Statistical data
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