About the Authors

Anouk N. A. van der Horst-Schrivers

Affiliation Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

Wim J. Sluiter

Affiliation Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

Anneke C. Muller Kobold

Affiliation Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

Bruce H. R. Wolffenbuttel

Affiliation Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

John T. M. Plukker

Affiliation Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

Peter H. Bisschop

Affiliation Academic Medical Center, University of Amsterdam, Department of Endocrinology, Amsterdam, the Netherlands

John M. de Klerk

Affiliation Meander Medical Center Amersfoort, Department of Nuclear Medicine, Amersfoort, the Netherlands

Imad Al Younis

Affiliation Leiden University Medical Center, Department of Nuclear Medicine and Molecular Imaging, Leiden, the Netherlands

Paul Lips

Affiliation VU University Medical Center, Department of Internal Medicine/Endocrinology, Amsterdam, the Netherlands

Jan W. Smit

Affiliation Radboud University Nijmegen Medical Center, Department of Internal Medicine, Nijmegen, the Netherlands

Adrienne H. Brouwers

Affiliation Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

Thera P. Links

t.p.links@umcg.nl

Affiliation Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

Competing Interests

On behalf of all authors, the authors would like to state that this study received funding from a commercial source the Genzyme Corporation: this money was used only to execute the study and not for personal use of any of the authors. This funding does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. No further competing interests exists by any of the authors which may have compromised the objectivity or validity of the research, analyses, or interpretations in the current manuscript.

Author Contributions

Conceived and designed the experiments: ANAH WJS ACMK BHRW JTMP PHB JMK IAY PL JWS AHB TPL. Performed the experiments: ANAH ACMK PHB JMK IAY PL JWS AHB TPL. Analyzed the data: ANAH WJS ACMK BHRW AHB TPL. Contributed reagents/materials/analysis tools: ANAH WJS ACMK BHRW AHB TPL. Wrote the paper: ANAH WJS ACMK BHRW JTMP PHB JMK IAY PL JWS AHB TPL.