High-Fat Diet-Induced Adiposity, Adipose Inflammation, Hepatic Steatosis and Hyperinsulinemia in Outbred CD-1 Mice

Mingming Gao; Yongjie Ma; Dexi Liu

doi:10.1371/journal.pone.0119784

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Peer-reviewed

Research Article

High-Fat Diet-Induced Adiposity, Adipose Inflammation, Hepatic Steatosis and Hyperinsulinemia in Outbred CD-1 Mice

Mingming Gao,

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America
⨯
Yongjie Ma,

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America
⨯
Dexi Liu

* E-mail: dliu@uga.edu

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America
⨯

High-Fat Diet-Induced Adiposity, Adipose Inflammation, Hepatic Steatosis and Hyperinsulinemia in Outbred CD-1 Mice

Mingming Gao,
Yongjie Ma,
Dexi Liu

Published: March 13, 2015
https://doi.org/10.1371/journal.pone.0119784

About the Authors

Mingming Gao

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America

Yongjie Ma

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America

Dexi Liu

* E-mail: dliu@uga.edu

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MG DL. Performed the experiments: MG YM. Analyzed the data: MG YM DL. Contributed reagents/materials/analysis tools: MG YM DL. Wrote the paper: MG DL.

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Mouse models
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Adipose tissue
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Obesity
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Brown adipose tissue
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Adipocytes
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Fatty liver
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Inflammation
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Gene expression
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