RNA-Seq Analysis Identifies New Genes Regulated by the Histone-Like Nucleoid Structuring Protein (H-NS) Affecting Vibrio cholerae Virulence, Stress Response and Chemotaxis

Hongxia Wang; Julio C. Ayala; Jorge A. Benitez; Anisia J. Silva

doi:10.1371/journal.pone.0118295

Loading metrics

Open Access

Peer-reviewed

Research Article

RNA-Seq Analysis Identifies New Genes Regulated by the Histone-Like Nucleoid Structuring Protein (H-NS) Affecting Vibrio cholerae Virulence, Stress Response and Chemotaxis

Hongxia Wang,

Affiliations Morehouse School of Medicine Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia, United States of America, State Key Laboratory for Infectious Disease Prevention and Control, and National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China
⨯
Julio C. Ayala,

Affiliation University of Alabama at Birmingham Department of Microbiology, Birmingham, Alabama, United States of America
⨯
Jorge A. Benitez,

Affiliation Morehouse School of Medicine Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia, United States of America
⨯
Anisia J. Silva

* E-mail: asilva-benitez@msm.edu

Affiliation Morehouse School of Medicine Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia, United States of America
⨯

RNA-Seq Analysis Identifies New Genes Regulated by the Histone-Like Nucleoid Structuring Protein (H-NS) Affecting Vibrio cholerae Virulence, Stress Response and Chemotaxis

Hongxia Wang,
Julio C. Ayala,
Jorge A. Benitez,
Anisia J. Silva

Published: February 13, 2015
https://doi.org/10.1371/journal.pone.0118295

About the Authors

Hongxia Wang

Affiliations Morehouse School of Medicine Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia, United States of America, State Key Laboratory for Infectious Disease Prevention and Control, and National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China

Julio C. Ayala

Affiliation University of Alabama at Birmingham Department of Microbiology, Birmingham, Alabama, United States of America

Jorge A. Benitez

Affiliation Morehouse School of Medicine Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia, United States of America

Anisia J. Silva

* E-mail: asilva-benitez@msm.edu

Affiliation Morehouse School of Medicine Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AJS JAB. Performed the experiments: HW JCA. Analyzed the data: AJS JAB HW JCA. Wrote the paper: AJS JAB.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Vibrio cholerae
Is the Subject Area "Vibrio cholerae" applicable to this article?

Thanks for your feedback.
El Tor
Is the Subject Area "El Tor" applicable to this article?

Thanks for your feedback.
Chemotaxis
Is the Subject Area "Chemotaxis" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Indoles
Is the Subject Area "Indoles" applicable to this article?

Thanks for your feedback.
Regulator genes
Is the Subject Area "Regulator genes" applicable to this article?

Thanks for your feedback.
Toxins
Is the Subject Area "Toxins" applicable to this article?

Thanks for your feedback.