About the Authors

Yoshihiro Kawano

b3wd1002@s.tohoku.ac.jp

Affiliations The Department of Biomedical Engineering, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Miyagi, Japan, Olympus Corporation, Shinjuku-Ku, Tokyo, Japan

Chino Otsuka

Affiliation Olympus Corporation, Shinjuku-Ku, Tokyo, Japan

James Sanzo

Affiliation Olympus Scientific Solutions Americas, Waltham, Massachusetts, United States of America

Christopher Higgins

Affiliation Olympus Scientific Solutions Americas, Waltham, Massachusetts, United States of America

Tatsuo Nirei

Affiliation Olympus Engineering, Hachioji, Tokyo, Japan

Tobias Schilling

Affiliation Olympus Soft Imaging Solutions GmbH, Münster, Germany

Takuji Ishikawa

Affiliation Department of Bioengineering and Robotics, Tohoku University, Sendai, Miyagi, Japan

Competing Interests

Olympus America Inc. and Olympus Corporation provided microscope equipment but was not a funder of, and did not influence the outcome of, the study. The VS120 WSI scanning system was used. Yoshihiro Kawano and Chino Otsuka are employed by Olympus Corporation, James Sanzo and Christopher Higgins are employed by Olympus America, Tatsuo Nirei by Olympus Engineering and Tobias Schilling by Olympus Soft Imaging Solutions GmbH. This particular microscope setup (VS120 with BX-DSU) is not available in the market. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: YK CO JS CH TN TS. Performed the experiments: YK CO JS CH. Analyzed the data: YK CO JS CH TS TI. Contributed reagents/materials/analysis tools: YK CO JS. Wrote the paper: YK CO JS CH TS TI.