About the Authors

Harumasa Nakazawa

Contributed equally to this work with: Harumasa Nakazawa, Marina Yamada

Affiliation Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

Marina Yamada

Contributed equally to this work with: Harumasa Nakazawa, Marina Yamada

Affiliations Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America, Shriners Hospitals for Children, Boston, Massachusetts, United States of America

Tomokazu Tanaka

Affiliation Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America

Joshua Kramer

Affiliation Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Yong-Ming Yu

Affiliations Shriners Hospitals for Children, Boston, Massachusetts, United States of America, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Alan J. Fischman

Affiliation Shriners Hospitals for Children, Boston, Massachusetts, United States of America

J. A. Jeevendra Martyn

Affiliations Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America, Shriners Hospitals for Children, Boston, Massachusetts, United States of America

Ronald G. Tompkins

Affiliations Shriners Hospitals for Children, Boston, Massachusetts, United States of America, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Masao Kaneki

mkaneki@helix.mgh.harvard.edu

Affiliations Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America, Shriners Hospitals for Children, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MK MY HN JK. Performed the experiments: MK MY HN TT JK. Analyzed the data: MK HN MY TT JK. Contributed reagents/materials/analysis tools: MK MY YMY AJF JAJM RGT. Wrote the paper: MK HN MY YMY AJF JAJM RGT JK.