About the Authors

Yinghong An

‡ These authors contributed equally to this work.

Affiliation Clinical Laboratory Center, Chinese PLA Air Force General Hospital, Haidian, Beijing 100142, PR China

Wanjun Guo

‡ These authors contributed equally to this work.

Affiliation Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China

Linna Li

Affiliation Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China

Chengwang Xu

Affiliation Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China

Dexuan Yang

Affiliation Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China

Shanshan Wang

Affiliation Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China

Yaxin Lu

Affiliation College of Pharmacy, The State Key Laboratory of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, PR China

Quan Zhang

Affiliation College of Pharmacy, The State Key Laboratory of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, PR China

Jiadai Zhai

Affiliation College of Pharmacy, The State Key Laboratory of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, PR China

Hongxia Fan

Affiliation College of Pharmacy, The State Key Laboratory of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, PR China

Chuanjiang Qiu

Affiliation Accendatech Co., Ltd., Tianjin 300384, PR China

Jie Qi

Affiliation Accendatech Co., Ltd., Tianjin 300384, PR China

Yue Chen

yuansj@nic.bmi.ac.cn (SY) yuechenayh@163.com (YC)

Affiliation Accendatech Co., Ltd., Tianjin 300384, PR China

Shoujun Yuan

yuansj@nic.bmi.ac.cn (SY) yuechenayh@163.com (YC)

Affiliation Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China

Competing Interests

Yue Chen is one of the founders of Accendatech Co., Ltd., which has a financial interest in DMAMCL. All other authors declare no competing financial interests. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YA WG SY YC. Performed the experiments: YA WG LL YL QZ JZ. Analyzed the data: YA WG CX YL. Contributed reagents/materials/analysis tools: DY SW HF CQ JQ. Wrote the paper: YA.