About the Authors

Mart Toots

Affiliation Institute of Technology, University of Tartu, Tartu, Tartumaa, Estonia

Andres Männik

Affiliation Icosagen Cell Factory OÜ, Ülenurme vald, Tartumaa, Estonia

Gaily Kivi

Affiliations Institute of Technology, University of Tartu, Tartu, Tartumaa, Estonia, Icosagen Cell Factory OÜ, Ülenurme vald, Tartumaa, Estonia

Mart Ustav Jr.

Affiliation Institute of Technology, University of Tartu, Tartu, Tartumaa, Estonia

Ene Ustav

Affiliation Estonian Biocentre, Tartu, Tartumaa, Estonia

Mart Ustav

mart.ustav@ut.ee

Affiliations Institute of Technology, University of Tartu, Tartu, Tartumaa, Estonia, Icosagen Cell Factory OÜ, Ülenurme vald, Tartumaa, Estonia, Estonian Academy of Sciences, Tallinn, Harjumaa, Estonia

Competing Interests

Although this work was done in collaboration between Icosagen Cell Factory OÜ and University of Tartu, Institute of Technology, this does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MT AM EU M. Ustav. Performed the experiments: MT AM GK M. Ustav Jr. Analyzed the data: MT AM GK M. Ustav Jr EU M. Ustav. Contributed to the writing of the manuscript: MT AM M. Ustav Jr EU M. Ustav.