About the Authors

Mark Richter

Affiliation Oncology R&D, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, Pennsylvania, United States of America

Tajhal Dayaram

Affiliation Department of Molecular Virology and Microbiology and Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

Aidan G. Gilmartin

Affiliation Oncology R&D, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, Pennsylvania, United States of America

Gopinath Ganji

Affiliation Oncology R&D, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, Pennsylvania, United States of America

Sandhya Kiran Pemmasani

Affiliation Ocimum Biosolutions Ltd., HUDA Techno Enclave, Hyderabad, AP, India

Harjeet Van Der Key

Affiliation Platform Technology & Science, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, Pennsylvania, United States of America

Jason M. Shohet

Affiliation Texas Children’s Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

Lawrence A. Donehower

larryd@bcm.edu (LAD); rakesh.2.kumar@gsk.com (RK)

Affiliation Department of Molecular Virology and Microbiology and Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

Rakesh Kumar

larryd@bcm.edu (LAD); rakesh.2.kumar@gsk.com (RK)

Affiliation Oncology R&D, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, Pennsylvania, United States of America

Competing Interests

Funding for the work was provided by GlaxoSmithKline, the employer of MR, AGG, GG, HVDK and RK at the time of the study. SKP is employed by Ocimum Biosolutions Ltd. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MR TD AGG GG HVDK JMS LAD RK. Performed the experiments: MR TD SKP HVDK. Analyzed the data: MR TD GG SKP HVDK AGG JMS LAD RK. Wrote the paper: MR TD GG SKP HVDK AGG JMS LAD RK.