SynPAnal: Software for Rapid Quantification of the Density and Intensity of Protein Puncta from Fluorescence Microscopy Images of Neurons

Eric Danielson; Sang H. Lee

doi:10.1371/journal.pone.0115298

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Open Access

Peer-reviewed

Research Article

SynPAnal: Software for Rapid Quantification of the Density and Intensity of Protein Puncta from Fluorescence Microscopy Images of Neurons

Eric Danielson,

Current address: University of Massachusetts Medical Center, University of Massachusetts Medical School, Worcester, Massachusetts.

Affiliation Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
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Sang H. Lee

* E-mail: shlee@mcw.edu

Affiliations Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯

SynPAnal: Software for Rapid Quantification of the Density and Intensity of Protein Puncta from Fluorescence Microscopy Images of Neurons

Eric Danielson,
Sang H. Lee

Published: December 22, 2014
https://doi.org/10.1371/journal.pone.0115298

About the Authors

Eric Danielson

Current address: University of Massachusetts Medical Center, University of Massachusetts Medical School, Worcester, Massachusetts.

Affiliation Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

Sang H. Lee

* E-mail: shlee@mcw.edu

Affiliations Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ED SHL. Performed the experiments: ED SHL. Analyzed the data: ED SHL. Contributed reagents/materials/analysis tools: ED. Wrote the paper: ED SHL. Developed software: ED.

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Neuronal dendrites
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Computer software
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Neurons
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Image analysis
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Synapses
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Fluorescence imaging
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Transfection
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Synaptic plasticity
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