STIM1 Positively Regulates the Ca2+ Release Activity of the Inositol 1,4,5-Trisphosphate Receptor in Bovine Aortic Endothelial Cells

Éric Béliveau; Vincent Lessard; Gaétan Guillemette

doi:10.1371/journal.pone.0114718

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Open Access

Peer-reviewed

Research Article

STIM1 Positively Regulates the Ca²⁺ Release Activity of the Inositol 1,4,5-Trisphosphate Receptor in Bovine Aortic Endothelial Cells

Éric Béliveau ,

Contributed equally to this work with: Éric Béliveau, Vincent Lessard

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, J1H 5N4
⨯
Vincent Lessard ,

Contributed equally to this work with: Éric Béliveau, Vincent Lessard

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, J1H 5N4
⨯
Gaétan Guillemette

* E-mail: gaetan.guillemette@usherbrooke.ca

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, J1H 5N4
⨯

STIM1 Positively Regulates the Ca²⁺ Release Activity of the Inositol 1,4,5-Trisphosphate Receptor in Bovine Aortic Endothelial Cells

Éric Béliveau,
Vincent Lessard,
Gaétan Guillemette

Published: December 15, 2014
https://doi.org/10.1371/journal.pone.0114718

About the Authors

Éric Béliveau

Contributed equally to this work with: Éric Béliveau, Vincent Lessard

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, J1H 5N4

Vincent Lessard

Contributed equally to this work with: Éric Béliveau, Vincent Lessard

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, J1H 5N4

Gaétan Guillemette

* E-mail: gaetan.guillemette@usherbrooke.ca

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, J1H 5N4

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EB VL GG. Performed the experiments: EB VL. Analyzed the data: EB VL GG. Contributed reagents/materials/analysis tools: GG. Wrote the paper: EB VL GG.

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Transfection
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Immunoprecipitation
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Endothelial cells
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Endoplasmic reticulum
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Small interfering RNA
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Antibodies
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Co-immunoprecipitation
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Intracellular receptors
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