About the Authors

James F. Burke

jamesbur@umich.edu

Affiliations Dept. of Neurology, University of Michigan, Ann Arbor, Michigan, United States of America, Robert Wood Johnson Clinical Scholars Program, University of Michigan, Ann Arbor, Michigan, United States of America, Center for Clinical Management Research, VAAAHS, Ann Arbor, Michigan, United States of America

Kenneth M. Langa

Affiliations Dept. of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America, Center for Clinical Management Research, VAAAHS, Ann Arbor, Michigan, United States of America, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America

Rodney A. Hayward

Affiliations Robert Wood Johnson Clinical Scholars Program, University of Michigan, Ann Arbor, Michigan, United States of America, Dept. of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America, Center for Clinical Management Research, VAAAHS, Ann Arbor, Michigan, United States of America

Roger L. Albin

Affiliations Dept. of Neurology, University of Michigan, Ann Arbor, Michigan, United States of America, Geriatric Research, Education, and Clinical Center, and Neurology Service, VAAAHS, Ann Arbor, Michigan, United States of America, Michigan Alzheimer Disease Center, University of Michigan, Ann Arbor, Michigan, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JFB KML RAH RLA. Performed the experiments: JFB. Analyzed the data: JFB. Contributed reagents/materials/analysis tools: JFB RAH. Wrote the paper: JFB KML RAH RLA. Design of the simulated population: JFB RAH KML. Validation of the simulated population: JFB RAH KML. Critical revision of the manuscript: KML RAH RLA.