About the Authors

Henrik Loe

Affiliations K.G. Jebsen Center of Exercise in Medicine at Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, Valnesfjord Rehabilitation Center, Valnesfjord, Norway

Sigurd Steinshamn

Affiliations K.G. Jebsen Center of Exercise in Medicine at Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, Department of Thoracic Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway

Ulrik Wisløff

ulrik.wisloff@ntnu.no

Affiliation K.G. Jebsen Center of Exercise in Medicine at Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway

Competing Interests

This study was funded in part by Roche Norway Incorporated Center. There are no disclosures to report or any conflicts of interest. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: UW. Performed the experiments: UW. Analyzed the data: HL SS UW. Contributed reagents/materials/analysis tools: HL SS UW. Wrote the paper: HL SS UW. Contributed substantially to design, analysis and interpretation of data, final approval of manuscript and was accountable for all aspects of the work: HL SS UW. Drafted manuscript: HL. Critical revision of manuscript for important intellectual content: SS UW. Conception and acquisition of work: UW.